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Neurotransmitters

Neurotransmitters
There are many neurotransmitters in the brain. Three which are known to affect depression are dopamine, norepinephrine, and serotonin. Some medicines for depression increase just one of these neurotransmitters, while others increase two or more.

This section shows the primary neurotransmitters thought to be important in depression and which medicines increase which neurotransmitters.

The following medications often help alleviate depression by enhancing the level of dopamine in the brain:

amphetamine (Adderall, Adderall XR)

buproprion (Wellbutrin, Wellbutrin SR)

dexmethylphenidate HCl (Focalin)

dextroamphetamine (Dexedrine, Dextrostat)

methlphenidate (Ritalin, Concerta)
The following medications often help alleviate depression by enhancing the level of norepinephrine in the brain:

atomoxetine HCl (Strattera)

buproprion (Wellbutrin, Wellbutrin SR)

dexmethylphenidate HCl (Focolin)

mirtazapine (Remeron)

nefazodone (Serzone)

venlafaxine (Effexor, Effexor XR)
The following medications often help alleviate depression by enhancing the level of serotonin in the brain:

citalopram (Celexa)

escitalopram (Lexapro)

fluoxetine (Prozac)

fluvoxamine (Luvox)

mirtazapine (Remeron)

nefazodone (Serzone)

paroxetine (Paxil)

sertraline (Zoloft)

venlafaxine (Effexor, Effexor XR)
With all medications it is important to discuss any questions you have with your physician, physician's assistant, or nurse.